Google Adsense ads are automatically targeted to the content of your website, but sometimes not all parts of your website are relevant to the main content of the page (for example text in side bar, header and etc.).
You may want Google Adsense to know more about your main content’s keywords so that Google Adsense can show more relevant ads.
Many people may have forgotten about what you can do and what you can’t do with Google Adsense’s advertisement on their web pages. Here are just some friendly reminders 
Invalid Clicks and Impressions – Do not click on your own ads! Encouraging clicks – Do not, in anyway, encourage your visitor to click on your Adsense’s ads …
Site Content – In short, no adults, no violants, no hates, no gambling, no casino, no alcohol and tobacco-related products, no illegal activities …
Site andAd Behavior – no pop up on site, no modification to Adsense code …
Ad Placement – maximum 3 ad units, 2 search boxes in one page and 3 link units in one page, no ad on any non-content-based pages, no ad on any pages that purposely display ads …
For more detail, please read Google Adsense Program Policies
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